|$0 My Commitment: $2,000.00|
I am thrilled to be riding in Pelotonia for the 3rd year. I have committed to ride 100 miles in August for Pelotonia, but this incredible grassroots movement is so much more than a bike ride.
We have all be touched by cancer in some way and the helplessness we feel watching our loved ones fight and struggle can be completely overwhelming. There is comfort in recognizing that there is a large community of people committed to make a change. ONE HUNDRED PERCENT OF EVERY SINGLE DOLLAR GOES DIRECTLY TO LIFE-SAVING CANCER RESEARCH. If you, like me, wondered what that actually looks like...here are 2 examples of the impact of YOUR Pelotonia funds.
My best friend lost her wonderful father to a battle with Glioblastoma. Glioblastoma is the most common type of malignant brain tumor, with most patients living just 12 to 15 months from the initial diagnosis. New molecular targets are urgently needed to make a significant improvements in patient survival. Thanks to Pelotonia’s Idea Grant Program, a research team recently revealed that a protein called SCAP is essential for activation of SREBP-1, a gene/protein known to have involvement in GBM growth. This study will focus on advancing knowledge of how cellular metabolism is “reprogrammed” in GBM. This knowledge could help identify promising new molecular targets for the disease.
My mother, grandmother, and several other wonderful friends and colleagues were able to overcome their battles with Breast Cancer but others have not been so lucky. Cancer activates specific cells that interfere with the immune system’s ability to kill cancer. A Pelotonia research team discovered that these cells – known as myeloid-derived suppressor cells (MDSC) – can be stopped with the drug ibrutinib, which targets and blocks Bruton’s tyrosine kinase. In preclinical studies, researchers also showed that this drug was most effective if given in combination with a second drug that activates immune-boosting T-cells called immune checkpoint inhibitors. Initial preclinical results showed a complete elimination of breast cancer tumors in 50 percent of subjects treated with the combination of ibrutinib and immune checkpoint inhibitors.
While we all may feel helpless in the fight against cancer, fundraising for Pelotonia is one small contribution we can make. If you would like to contribute to my ride, 100% of your donation will go directly towards life-saving cancer research at The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute.
Thank you for your consideration!
|07/30/2019||AJ & James||$200.00|
|07/30/2019||Rita & Amy||$25.00|
|07/30/2019||Tyler and Amelia Hennen||$50.00|
|07/25/2019||Meg and Matt Herring||$25.00|
|07/25/2019||John & Dani||$100.00|
|07/16/2019||Card & Canvas||$5.00|
|06/22/2019||Bearett, Wyatt, Jeff & Amanda Golden||$50.00|
|06/11/2019||Pelotonia on the Patio||$10.00|
|06/04/2019||Kristy, Oscar, Penelope & Eleanor||$50.00|